Advanced cardiac risk analysis, genetic testing, imaging, and metabolic testing to improve both health and longevity.
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Dr. Ghalichi provides a comprehensive, personalized longevity evaluation, offering advanced cardiac risk analysis, genetic testing, family history review, cardiac and vascular imaging, and lipid/metabolic testing. This integrative approach surpasses standard care, assessing disease risk and crafting a plan to improve both health and longevity.
Key Areas of Focus
This is the global top killer of both men and women. This evaluation uses advanced testing from best-in-class labs such as Boston Heart and Cleveland HeartLab to reveal whether arterial plaque is forming, at what rate, and if there is a genetic cause. Cardiac imaging is utilized to determine your status of disease now. A thorough plan is made for intervention if a problem is found so that you do not have advanced stages of disease years later.
Neurodegenerative disorders—led by Alzheimer's disease—now rank among the top global causes of death, yet their warning signs can emerge decades before memory slips. This evaluation combines APOE genotyping, micronutrient profiling, and central-nervous-system cholesterol turnover analysis with the ultra-sensitive p-tau-217 blood test—an early indicator of Alzheimer-type tau pathology.
Insulin resistance underpins many metabolic disorders and often precedes overt diabetes by years. This evaluation quantifies insulin sensitivity, screens for MTHFR and other methylation variants, and integrates additional metabolic markers to uncover hidden risk. Findings are translated into an individualized treatment roadmap that targets root causes and optimizes metabolic resilience.
Early detection is always a better prognosis than late detection. In addition to routine assays such as PSA, this evaluation offers cutting-edge surveillance options — multicancer liquid biopsy testing (e.g., Grail GALLERI) and high-resolution whole-body MRI screening — to uncover malignancies at their earliest, most treatable stage.
The evaluation begins with an in-depth consultation with Dr. Ghalichi, where you will discuss your symptoms, medical history, goals, nutrition, sleep, exercise, family history, supplements, and risk factors. This is followed by a physical examination, along with cardiac, vascular, and liver imaging. A fasting blood draw is then performed. Two weeks later, Dr. Ghalichi reviews all results with you and develops a personalized plan based on your findings.
Estimated time: 90 minutes
Arrive fasting for at least 6 hours. Water is ok and encouraged. In-person at the Cedars-Sinai Medical Office Tower in Los Angeles.
Estimated time: 60 minutes
At least two weeks after the initial appointment. Can be in-person or via video conferencing.
Philips EPIQ Elite Ultrasound System (Netherlands) for superior imaging quality and advanced intelligence.
The integration of artificial intelligence helps in enhancing diagnostic confidence with more accurate and efficient analysis.
These tests are operator dependent. Dr. Ghalichi performs the scans himself and has completed an extra fellowship in cardiovascular imaging.
No Radiation Exposure AI-Driven Tools
Labs are drawn at the appointment, packed on ice, and shipped overnight to Boston Heart Diagnostics. Results are reviewed at a follow-up appointment in two weeks.
Includes ApoB, Lipoprotein (a), and many other markers for an in-depth evaluation of cardiovascular risk.
Assessment of APOE genotype to evaluate your genetic predisposition to Alzheimer's disease.
Testing for MTHFR gene mutations that affect methylation, along with homocysteine levels.
Detailed testing to assess your body's response to insulin, a critical factor in metabolic health.
Lab Partners
This test examines the arteries in the neck, allowing visualization of plaque without radiation exposure. This is the source of most strokes, and can be detected years before symptoms occur. Dr. Ghalichi performs this operator-dependent scan himself, using Philips Healthcare software to measure the carotid intima-media thickness (CIMT) with high precision.
A transthoracic echocardiogram is an ultrasound that evaluates your heart's structure and function, providing detailed images to assess how well the heart muscle, valves, and chambers are working. It measures heart wall thickness, chamber size, and valve function, helping to detect any abnormalities. Doppler ultrasound is used to check blood flow.
Liver fat (visceral fat) is metabolically harmful. This test is performed via ultrasound using FDA-approved software analysis from Philips Healthcare, validated against MRI and liver biopsy to measure liver fat—a key factor in metabolic health and early detection of fatty liver disease.
This test screens for aneurysms in the abdominal aorta, critical for early detection and management of this potentially life-threatening condition.
The GE Healthcare MAC 5 Machine is utilized, featuring advanced algorithms for age- and gender-specific analysis to identify cardiac electrical and rhythm abnormalities.
Not just to assess your risk of cardiovascular disease in the future, but to take action now and alter the course of disease progression. Based on your risk, tests such as a CT Coronary Calcium Score or CT Coronary Angiogram with AI plaque analysis may be recommended. Modern pharmacotherapies, like PCSK9 inhibitors (e.g., Repatha, Leqvio), might be prescribed for individuals at elevated risk.
Non-medication strategies are formulated to reverse insulin resistance. If the condition is severe, medications like GLP-1 agonists (e.g., semaglutide, tirzepatide, Ozempic, Zepbound) or SGLT2 inhibitors (e.g., Jardiance, Farxiga) may be considered to improve metabolic health.
Exploration of secondary causes is essential. Non-medication interventions are prioritized. Pharmacotherapy may be initiated or adjusted based on blood pressure severity and individual patient needs.
For individuals with MTHFR mutations affecting methylation, personalized dietary and supplement plans are designed to optimize methylation pathways and improve metabolic function.
For those carrying the APOE e4 gene variant, increasing their genetic risk for Alzheimer's disease, a personalized, evidence-based prevention strategy is crafted to reduce the likelihood of cognitive decline.
High-sensitivity assays are used to detect inflammation. A thorough analysis of micronutrient levels, including essential vitamins and minerals such as Omega-3, Vitamin D, and CoQ10, is performed. A tailored plan is created to address deficiencies.
Focuses on optimizing your diet based on your genetic profile and metabolic needs to improve health, longevity, and performance.
Tailored exercise programs designed to maximize cardiovascular and muscular health, promote longevity, and reduce the risk of chronic diseases.
Improving sleep quality and duration to enhance recovery, cognitive function, and overall well-being.
Strategic use of scientifically-backed medications, hormones, and supplements to optimize bodily functions and promote health longevity.
Featured Podcast
In this episode of the SHE MD Podcast, Dr. Ghalichi shares expert insights on preventing heart attacks, optimizing heart health, and longevity-focused strategies.
Contact us to book your comprehensive longevity evaluation.
